TXNRD1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12022a
Background:
This gene encodes a member of the family of pyridinenucleotide oxidoreductases. This protein reduces thioredoxins aswell as other substrates, and plays a role in selenium metabolismand protection against oxidative stress. The functional enzyme isthought to be a homodimer which uses FAD as a cofactor. Eachsubunit contains a selenocysteine (Sec) residue which is requiredfor catalytic activity. The selenocysteine is encoded by the UGAcodon that normally signals translation termination. The 3' UTR ofselenocysteine-containing genes have a common stem-loop structure,the sec insertion sequence (SECIS), that is necessary for therecognition of UGA as a Sec codon rather than as a stop signal.Alternative splicing results in several transcript variantsencoding the same or different isoforms.
Other Names:
Thioredoxin reductase 1, cytoplasmic, TR, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF
Gene Name: TXNRD1 (HGNC:12437)
Gene ID: 7296
Primary Accession: Q16881
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the family of pyridinenucleotide oxidoreductases. This protein reduces thioredoxins aswell as other substrates, and plays a role in selenium metabolismand protection against oxidative stress. The functional enzyme isthought to be a homodimer which uses FAD as a cofactor. Eachsubunit contains a selenocysteine (Sec) residue which is requiredfor catalytic activity. The selenocysteine is encoded by the UGAcodon that normally signals translation termination. The 3' UTR ofselenocysteine-containing genes have a common stem-loop structure,the sec insertion sequence (SECIS), that is necessary for therecognition of UGA as a Sec codon rather than as a stop signal.Alternative splicing results in several transcript variantsencoding the same or different isoforms.
Other Names:
Thioredoxin reductase 1, cytoplasmic, TR, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF
Gene Name: TXNRD1 (HGNC:12437)
Gene ID: 7296
Primary Accession: Q16881
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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