TYK2 antibody (clone 6G12), anti-human

Background:
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Other Names:
Non-receptor tyrosine-protein kinase TYK2, TYK2

Antigen Type:
Recombinant Protein

Gene Name: TYK2
Gene ID: 7297
NCBI Accession: NP_003322.3
Primary Accession: P29597
Other Accession: BC014243
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .