Tyro3 (clone 7A10C11, 7A10G4), anti-human
€539.00
In stock
SKU
252662
Protein Family: Enzymes, Protein Kinases, Receptors and Channels
Pathway and Disease: Cell Growth and Death
Description:
Tyro3 (Tyrosine-protein kinase receptor TYRO3) is a 890-amino acid protein (~98kDa) is a tyrosine-protein kinase. It belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer. Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation and phagocytosis. Tyro3 is expressed at high levels during postnatal development and in the adult in the cortex. Tyro3 and Gas6 have neurotrophic roles in the nervous system. In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Alternate Names: Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase byk, BYK, DTK, RSE, SKY, TYRO3
Application Notes: WB: 1:500-1:2000
Accession No.: Q06418
Antigen: Purified recombinant fragment of Tyro3 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cell Growth and Death
Description:
Tyro3 (Tyrosine-protein kinase receptor TYRO3) is a 890-amino acid protein (~98kDa) is a tyrosine-protein kinase. It belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer. Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation and phagocytosis. Tyro3 is expressed at high levels during postnatal development and in the adult in the cortex. Tyro3 and Gas6 have neurotrophic roles in the nervous system. In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Alternate Names: Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase byk, BYK, DTK, RSE, SKY, TYRO3
Application Notes: WB: 1:500-1:2000
Accession No.: Q06418
Antigen: Purified recombinant fragment of Tyro3 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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