Tyrosine Hydroxylase, TH (clone N37), anti-human, mouse, rabbit
€0.00
In stock
SKU
BMA1044
Catalog Number: BMA1044
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, rat, rabbit
Application(s): WB, IHC-P, IHC-Fr
Request Information
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, rat, rabbit
Application(s): WB, IHC-P, IHC-Fr
Request Information
Background:
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system (CNS), peripheral symphatic neurons and the adrenal medulla. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. It also can be inhibited by the drug α-methyl-para-tyrosine (metirosine). This drug is rarely used and can cause depression, but it is useful in treating pheochromocytoma and also resistant hypertension.
Immunogen:
Purified rat TH.
Recommended Application:
Western Blot, WB(1:200-1000); Immunohistochemistry, IHC-P (1:20-200); Immunohistochemistry, IHC-Fr (1:20-200)
Product Form: Liquid
Purification: Protein A or Protein G purified
Storage Buffer: In TBS (0.1M), 30% Glycerol and 0.01% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system (CNS), peripheral symphatic neurons and the adrenal medulla. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. It also can be inhibited by the drug α-methyl-para-tyrosine (metirosine). This drug is rarely used and can cause depression, but it is useful in treating pheochromocytoma and also resistant hypertension.
Immunogen:
Purified rat TH.
Recommended Application:
Western Blot, WB(1:200-1000); Immunohistochemistry, IHC-P (1:20-200); Immunohistochemistry, IHC-Fr (1:20-200)
Product Form: Liquid
Purification: Protein A or Protein G purified
Storage Buffer: In TBS (0.1M), 30% Glycerol and 0.01% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review