U2AF2 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7326
Background:
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alternative Name:
hU2AF(65), hU2AF65, Splicing factor U2AF 65 kDa subunit, U2 auxiliary factor 65 kDa subunit, U2 small nuclear ribonucleoprotein auxiliary factor (65kD), U2 small nuclear RNA auxiliary factor 2, U2 snRNP auxiliary factor large subunit, U2AF2, U2AF2_HUMAN, U2AF65,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100, IP: 1:50 - 1:200
Specificity: U2AF2 polyclonal antibody detects endogenous levels of U2AF2 protein.
Immunogen:
Recombinant full length Human U2AF2.
MW: ~53 kDa
Swis Prot.: P26368
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alternative Name:
hU2AF(65), hU2AF65, Splicing factor U2AF 65 kDa subunit, U2 auxiliary factor 65 kDa subunit, U2 small nuclear ribonucleoprotein auxiliary factor (65kD), U2 small nuclear RNA auxiliary factor 2, U2 snRNP auxiliary factor large subunit, U2AF2, U2AF2_HUMAN, U2AF65,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100, IP: 1:50 - 1:200
Specificity: U2AF2 polyclonal antibody detects endogenous levels of U2AF2 protein.
Immunogen:
Recombinant full length Human U2AF2.
MW: ~53 kDa
Swis Prot.: P26368
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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