Uba5 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2186b
Background:
Various ubiquitin-like (UBL) post-translational modifiers contribute critically to the protein degradation pathway. These UBLs are covalently linked to most target proteins through an enzymatic cascade analogous to ubiquitylation, consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. Uba5 is an E1-like enzyme that belongs to the ubiquitin-activating enzyme family, and activates UFM1, a novel ubiquitin-fold modifier.
Other Names:
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1, UBA5, UBE1DC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2186b was selected from the C-term region of human Uba5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBA5 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:23230}
Gene ID: 79876
Primary Accession: Q9GZZ9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Various ubiquitin-like (UBL) post-translational modifiers contribute critically to the protein degradation pathway. These UBLs are covalently linked to most target proteins through an enzymatic cascade analogous to ubiquitylation, consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. Uba5 is an E1-like enzyme that belongs to the ubiquitin-activating enzyme family, and activates UFM1, a novel ubiquitin-fold modifier.
Other Names:
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1, UBA5, UBE1DC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2186b was selected from the C-term region of human Uba5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBA5 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:23230}
Gene ID: 79876
Primary Accession: Q9GZZ9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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