UBA7 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14193a
Background:
The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s,ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E1ubiquitin-activating enzyme family. The encoded enzyme is aretinoid target that triggers promyelocytic leukemia (PML)/retinoicacid receptor alpha (RARalpha) degradation and apoptosis in acutepromyelocytic leukemia, where it is involved in the conjugation ofthe ubiquitin-like interferon-stimulated gene 15 protein. [providedby RefSeq].
Other Names:
Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog, UBA7, UBE1L, UBE2
Gene Name: UBA7 {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:12471}
Gene ID: 7318
Primary Accession: P41226
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s,ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E1ubiquitin-activating enzyme family. The encoded enzyme is aretinoid target that triggers promyelocytic leukemia (PML)/retinoicacid receptor alpha (RARalpha) degradation and apoptosis in acutepromyelocytic leukemia, where it is involved in the conjugation ofthe ubiquitin-like interferon-stimulated gene 15 protein. [providedby RefSeq].
Other Names:
Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog, UBA7, UBE1L, UBE2
Gene Name: UBA7 {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:12471}
Gene ID: 7318
Primary Accession: P41226
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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