UBE2A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70890
Background:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
Alternative Name:
UBC2, HHR6A, MRXSN, RAD6A, MRXS30,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: UBE2A polyclonal antibody detects endogenous levels of UBE2A protein.
Immunogen:
Recombinant protein of human UBE2A.
MW: ~ 17 kDa
Swis Prot.: P49459
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
Alternative Name:
UBC2, HHR6A, MRXSN, RAD6A, MRXS30,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: UBE2A polyclonal antibody detects endogenous levels of UBE2A protein.
Immunogen:
Recombinant protein of human UBE2A.
MW: ~ 17 kDa
Swis Prot.: P49459
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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