UBE2C monoclonal (C-term), anti-human

UBE2C monoclonal (C-term), anti-human

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In stock
SKU
AC-AM8672b
Catalog Number: AC-AM8672b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 2001CT211.37.61
Applications: WB
Datasheet

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Background:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Other Names:
Ubiquitin-conjugating enzyme E2 C, 6.3.2.19, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C, UBE2C, UBCH10

Target/Specificity:
This UBE2C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 137~172 amino acids from the C-terminal region of human UBE2C.

Antigen Type: Synthesized Peptide

Gene Name: UBE2C
Gene ID: 11065
Primary Accession: O00762
Other Accession: Q32PA5; Q4R9D1; Q9D1C1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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