UBE2D1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7332
Background:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
E2(17)KB1, SFT, Stimulator of Fe transport, UB2D1_HUMAN, UBC 4/5, UBC4/5, UBC4/5 homolog, UBC4/5, S. cerevisiae, homolog of, UBCH 5, UBCH 5A, UbcH5, UBCH5A, Ube2d1, Ubiquitin carrier protein, Ubiquitin carrier protein D1, Ubiquitin conjugating enzyme E2 17 kDa 1, Ubiquitin conjugating enzyme E2 D1, Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast), Ubiquitin conjugating enzyme E2D 1, Ubiquitin conjugating enzyme UBCH5A, Ubiquitin protein ligase D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E2(17)KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: UBE2D1 polyclonal antibody detects endogenous levels of UBE2D1 protein.
Immunogen:
Recombinant full length Human UBE2D1.
MW: ~17 kDa
Swis Prot.: P51668
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
E2(17)KB1, SFT, Stimulator of Fe transport, UB2D1_HUMAN, UBC 4/5, UBC4/5, UBC4/5 homolog, UBC4/5, S. cerevisiae, homolog of, UBCH 5, UBCH 5A, UbcH5, UBCH5A, Ube2d1, Ubiquitin carrier protein, Ubiquitin carrier protein D1, Ubiquitin conjugating enzyme E2 17 kDa 1, Ubiquitin conjugating enzyme E2 D1, Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast), Ubiquitin conjugating enzyme E2D 1, Ubiquitin conjugating enzyme UBCH5A, Ubiquitin protein ligase D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E2(17)KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: UBE2D1 polyclonal antibody detects endogenous levels of UBE2D1 protein.
Immunogen:
Recombinant full length Human UBE2D1.
MW: ~17 kDa
Swis Prot.: P51668
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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