UBE2L3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70601
Background:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
Alternative Name:
E2-F1, L-UBC, UBCH7, UbcM4,
Application Dilution: WB: 1:1000 - 1:2000, IHC: 1:50 - 1:100
Specificity: UBE2L3 polyclonal antibody detects endogenous levels of UBE2L3 protein.
Immunogen:
Recombinant protein of human UBE2L3.
MW: ~ 18 kDa
Swis Prot.: P68036
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
Alternative Name:
E2-F1, L-UBC, UBCH7, UbcM4,
Application Dilution: WB: 1:1000 - 1:2000, IHC: 1:50 - 1:100
Specificity: UBE2L3 polyclonal antibody detects endogenous levels of UBE2L3 protein.
Immunogen:
Recombinant protein of human UBE2L3.
MW: ~ 18 kDa
Swis Prot.: P68036
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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