UBE4B Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2111a
Background:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
Other Names:
Ubiquitin conjugation factor E4 B, 632-, UBE4B (HGNC:12500)
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2111a was selected from the N-term region of human UBE4B . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBE4B (HGNC:12500)
Gene ID: 10277
Primary Accession: O95155
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
Other Names:
Ubiquitin conjugation factor E4 B, 632-, UBE4B (HGNC:12500)
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2111a was selected from the N-term region of human UBE4B . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UBE4B (HGNC:12500)
Gene ID: 10277
Primary Accession: O95155
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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