Ubiquitin (clone ), anti-human, mouse, rat

Background:
Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lysine 48 of one ubiquitin molecule and the carboxy-terminus of a neighboring ubiquitin molecule.

Alternative Name:
Polyubiquitin-B, Ubiquitin, UBB, Polyubiquitin-C, UBC, RPS27A, UBA80, UBCEP1, CEP52, UBA52, UBCEP2

Application Dilution: WB: 1:1000-1:2000, ICC: 1:50-1:200, IHC: 1:200-1:500, FC: 1:50-1:100

Specificity: This antibody detects ubiquitin, polyubiquitin and ubiquitinated proteins.

Immunogen:
Recombinant antibody.

MW: ~ *8 kDa or Uncertain

Swis Prot.: P0CG47/P0CG48/P62979/P62987

Purification & Purity:
Protein A affinity purified

Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.