UBR1 antibody (clone 2F5), anti-human
€435.00
In stock
SKU
AC-AT4450a
Catalog Number: AC-AT4450a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT4450a">Request Information
Background:
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.
Other Names:
E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1
Antigen Type:
Recombinant Protein
Gene Name: UBR1 {ECO:0000303|PubMed:15317757, ECO:0000312|HGNC:HGNC:16808}
Gene ID: 197131
NCBI Accession: NP_777576.1
Primary Accession: Q8IWV7
Other Accession: NM_17491
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.
Other Names:
E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1
Antigen Type:
Recombinant Protein
Gene Name: UBR1 {ECO:0000303|PubMed:15317757, ECO:0000312|HGNC:HGNC:16808}
Gene ID: 197131
NCBI Accession: NP_777576.1
Primary Accession: Q8IWV7
Other Accession: NM_17491
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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