UBTF antibody (clone 1A2), anti-human, rat
€435.00
In stock
SKU
AC-AT4454a
Catalog Number: AC-AT4454a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, Ehttps://www.abcepta.com/products/pdf_download/AT4454a-UBTF-Antibody-monoclonal-M03">Request Information AC-AT4454a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, Ehttps://www.abcepta.com/products/pdf_download/AT4454a-UBTF-Antibody-monoclonal-M03">Request Information AC-AT4454a">Request Information
Background:
Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).
Other Names:
Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1, UBTF, UBF, UBF1
Antigen Type:
Recombinant Protein
Gene Name: UBTF
Gene ID: 7343
NCBI Accession: NP_001070151.1;NP_001070152.1;NP_055048.1
Primary Accession: P17480
Other Accession: NM_014233
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).
Other Names:
Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1, UBTF, UBF, UBF1
Antigen Type:
Recombinant Protein
Gene Name: UBTF
Gene ID: 7343
NCBI Accession: NP_001070151.1;NP_001070152.1;NP_055048.1
Primary Accession: P17480
Other Accession: NM_014233
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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