UCP1 antibody (clone 400000), anti-human
€435.00
In stock
SKU
AC-AT4458a
Catalog Number: AC-AT4458a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4458a">Request Information
Background:
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Other Names:
Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin, UCP1, SLC25A7, UCP
Antigen Type:
Recombinant Protein
Gene Name: UCP1 (HGNC:12517)
Gene ID: 7350
NCBI Accession: NP_068605.1
Primary Accession: P25874
Other Accession: NM_021833
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Other Names:
Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin, UCP1, SLC25A7, UCP
Antigen Type:
Recombinant Protein
Gene Name: UCP1 (HGNC:12517)
Gene ID: 7350
NCBI Accession: NP_068605.1
Primary Accession: P25874
Other Accession: NM_021833
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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