UCP3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP18132c
Background:
Mitochondrial uncoupling proteins (UCP) are members of thelarger family of mitochondrial anion carrier proteins (MACP). UCPsseparate oxidative phosphorylation from ATP synthesis with energydissipated as heat, also referred to as the mitochondrial protonleak. UCPs facilitate the transfer of anions from the inner to theouter mitochondrial membrane and the return transfer of protonsfrom the outer to the inner mitochondrial membrane. They alsoreduce the mitochondrial membrane potential in mammalian cells. Thedifferent UCPs have tissue-specific expression; this gene isprimarily expressed in skeletal muscle. This gene's protein productis postulated to protect mitochondria against lipid-inducedoxidative stress. Expression levels of this gene increase whenfatty acid supplies to mitochondria exceed their oxidation capacityand the protein enables the export of fatty acids frommitochondria. UCPs contain the three solcar protein domainstypically found in MACPs. Two splice variants have been found forthis gene.
Other Names:
Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, UCP3, SLC25A9
Gene Name: UCP3 {ECO:0000303|PubMed:9180264, ECO:0000312|HGNC:HGNC:12519}
Gene ID: 7352
Primary Accession: P55916
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Mitochondrial uncoupling proteins (UCP) are members of thelarger family of mitochondrial anion carrier proteins (MACP). UCPsseparate oxidative phosphorylation from ATP synthesis with energydissipated as heat, also referred to as the mitochondrial protonleak. UCPs facilitate the transfer of anions from the inner to theouter mitochondrial membrane and the return transfer of protonsfrom the outer to the inner mitochondrial membrane. They alsoreduce the mitochondrial membrane potential in mammalian cells. Thedifferent UCPs have tissue-specific expression; this gene isprimarily expressed in skeletal muscle. This gene's protein productis postulated to protect mitochondria against lipid-inducedoxidative stress. Expression levels of this gene increase whenfatty acid supplies to mitochondria exceed their oxidation capacityand the protein enables the export of fatty acids frommitochondria. UCPs contain the three solcar protein domainstypically found in MACPs. Two splice variants have been found forthis gene.
Other Names:
Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, UCP3, SLC25A9
Gene Name: UCP3 {ECO:0000303|PubMed:9180264, ECO:0000312|HGNC:HGNC:12519}
Gene ID: 7352
Primary Accession: P55916
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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