UGCGL1 Antibody (C-term) Blocking Peptide

Background:
UGCGL1 recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Other Names:
UDP-glucose:glycoprotein glucosyltransferase 1, UGT1, hUGT1, 241-, UDP--Glc:glycoprotein glucosyltransferase, UDP-glucose ceramide glucosyltransferase-like 1, UGGT1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13145b was selected from the C-term region of UGCGL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: UGGT1

Gene ID: 56886
Primary Accession: Q9NYU2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.