UGT3A2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8994
Background:
UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecules, thereby regulating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecules and facilitates their entry into aqueous compartments and, ultimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT3A family of isoenzymes are expressed in liver and kidney, and to a lesser, in the gastrointestinal tract. UGT3A2 (UDP glycosyltransferase 3 family, polypeptide A2) is a 523 amino acid single-pass type I membrane protein that belongs to the UDP-glycosyltransferase family. It has been suggested that members of the UGT3A family may have an important role in the metabolism and elimination of ursodeoxycholic acid, a metabolic byproduct of intestinal bacteria.
Alternative Name:
UDP-glucuronosyltransferase 3A2, UDPGT 3A2, UGT3A2, PSEC0073, UNQ842/PRO1780
Application Dilution: WB: 1:500 - 1:2000
Specificity: UGT3A2 polyclonal antibody detects endogenous levels of UGT3A2 protein.
Immunogen:
Recombinant full length Human UGT3A2.
MW: ~ 60kDa
Swis Prot.: Q3SY77
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecules, thereby regulating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecules and facilitates their entry into aqueous compartments and, ultimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT3A family of isoenzymes are expressed in liver and kidney, and to a lesser, in the gastrointestinal tract. UGT3A2 (UDP glycosyltransferase 3 family, polypeptide A2) is a 523 amino acid single-pass type I membrane protein that belongs to the UDP-glycosyltransferase family. It has been suggested that members of the UGT3A family may have an important role in the metabolism and elimination of ursodeoxycholic acid, a metabolic byproduct of intestinal bacteria.
Alternative Name:
UDP-glucuronosyltransferase 3A2, UDPGT 3A2, UGT3A2, PSEC0073, UNQ842/PRO1780
Application Dilution: WB: 1:500 - 1:2000
Specificity: UGT3A2 polyclonal antibody detects endogenous levels of UGT3A2 protein.
Immunogen:
Recombinant full length Human UGT3A2.
MW: ~ 60kDa
Swis Prot.: Q3SY77
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review