UHRF1 (N-term (clone 1H9-D3-E11), anti-human, mouse

Background:
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: hNP95, hUHRF1, huNp95, ICBP90, Np95, RNF106, TDRD22

Cellular Location: Nucleus

Immunogen:
Purified recombinant human UHRF1 protein fragments expressed in E.coil.

Gene Symbol: UHRF1(N-term)

Gene ID: 29128

Swiss prot: Q96T88

Calculated MW: 90kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.