UNC13B Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP13116a
Background:
This gene is expressed in the kidney cortical epithelialcells and is upregulated by hyperglycemia. The encoded proteinshares a high level of similarity to the rat homolog, and contains3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemiaincreases the levels of diacylglycerol, which has been shown toinduce apoptosis in cells transfected with this gene and thuscontribute to the renal cell complications of hyperglycemia.Studies in other species also indicate a role for this protein inthe priming step of synaptic vesicle exocytosis. [provided byRefSeq].
Other Names:
Protein unc-13 homolog B, Munc13-2, munc13, UNC13B, UNC13
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13116a was selected from the N-term region of UNC13B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UNC13B (HGNC:12566)
Gene ID: 10497
Primary Accession: O14795
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is expressed in the kidney cortical epithelialcells and is upregulated by hyperglycemia. The encoded proteinshares a high level of similarity to the rat homolog, and contains3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemiaincreases the levels of diacylglycerol, which has been shown toinduce apoptosis in cells transfected with this gene and thuscontribute to the renal cell complications of hyperglycemia.Studies in other species also indicate a role for this protein inthe priming step of synaptic vesicle exocytosis. [provided byRefSeq].
Other Names:
Protein unc-13 homolog B, Munc13-2, munc13, UNC13B, UNC13
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13116a was selected from the N-term region of UNC13B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UNC13B (HGNC:12566)
Gene ID: 10497
Primary Accession: O14795
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review