UNC13D antibody (clone 2C7), anti-human
€435.00
In stock
SKU
AC-AT4470a
Catalog Number: AC-AT4470a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4470a">Request Information
Background:
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Other Names:
Protein unc-13 homolog D, Munc13-4, UNC13D
Antigen Type:
Recombinant Protein
Gene Name: UNC13D
Gene ID: 201294
NCBI Accession: NP_954712.1
Primary Accession: Q70J99
Other Accession: NM_199242
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Other Names:
Protein unc-13 homolog D, Munc13-4, UNC13D
Antigen Type:
Recombinant Protein
Gene Name: UNC13D
Gene ID: 201294
NCBI Accession: NP_954712.1
Primary Accession: Q70J99
Other Accession: NM_199242
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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