UPF2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP10692c
Background:
UPF2 is a protein that is part of apost-splicing multiprotein complex involved in both mRNA nuclearexport and mRNA surveillance. mRNA surveillance detects exportedmRNAs with truncated open reading frames and initiatesnonsense-mediated mRNA decay (NMD). When translation ends upstreamfrom the last exon-exon junction, this triggers NMD to degrademRNAs containing premature stop codons. This protein is located inthe perinuclear area. It interacts with translation release factorsand the proteins that are functional homologs of yeast Upf1p andUpf3p.
Other Names:
Regulator of nonsense transcripts 2, Nonsense mRNA reducing factor 2, Up-frameshift suppressor 2 homolog, hUpf2, UPF2, KIAA1408, RENT2
Gene Name: UPF2 (HGNC:17854)
Gene ID: 26019
Primary Accession: Q9HAU5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
UPF2 is a protein that is part of apost-splicing multiprotein complex involved in both mRNA nuclearexport and mRNA surveillance. mRNA surveillance detects exportedmRNAs with truncated open reading frames and initiatesnonsense-mediated mRNA decay (NMD). When translation ends upstreamfrom the last exon-exon junction, this triggers NMD to degrademRNAs containing premature stop codons. This protein is located inthe perinuclear area. It interacts with translation release factorsand the proteins that are functional homologs of yeast Upf1p andUpf3p.
Other Names:
Regulator of nonsense transcripts 2, Nonsense mRNA reducing factor 2, Up-frameshift suppressor 2 homolog, hUpf2, UPF2, KIAA1408, RENT2
Gene Name: UPF2 (HGNC:17854)
Gene ID: 26019
Primary Accession: Q9HAU5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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