UPK1A Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP9225b
Background:
The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Other Names:
Uroplakin-1a, UP1a, Tetraspanin-21, Tspan-21, Uroplakin Ia, UPIa, UPKa, UPK1A, TSPAN21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9225b was selected from the C-term region of human UPK1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UPK1A
Gene ID: 11045
Primary Accession: O00322
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Other Names:
Uroplakin-1a, UP1a, Tetraspanin-21, Tspan-21, Uroplakin Ia, UPIa, UPKa, UPK1A, TSPAN21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9225b was selected from the C-term region of human UPK1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UPK1A
Gene ID: 11045
Primary Accession: O00322
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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