UPK1B antibody (clone 10), anti-human

UPK1B antibody (clone 10), anti-human

€435.00
In stock
SKU
AC-AT4474a
Catalog Number: AC-AT4474a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Background:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

Other Names:
Uroplakin-1b, UP1b, Tetraspanin-20, Tspan-20, Uroplakin Ib, UPIb, UPK1B, TSPAN20

Antigen Type:
Recombinant Protein

Gene Name: UPK1B
Gene ID: 7348
NCBI Accession: NP_008883.2
Primary Accession: O75841
Other Accession: NM_006952
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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