UQCRC1 polyclonal, anti-human, mouse, rat, monkey
€388.00
In stock
SKU
BS70539
Background:
UQCRC1, or Ubiquinol-cytochrome-c reductase complex core protein 1, is a core subunit of the mitochondrial respiratory complex III. It is the largest nuclear encoded subunit of the complex. UQCRC1 plays a key role in mitochondria-to-nucleus retrograde response and is involved in the mitochondrial proton gradient formation. It has also shown to interact with Nogo, an inhibitor of neurite growth after spinal cord injury. UQCRC1 has been found at high expression levels in breast and ovarian tumors, positively correlating with Cox-2 expression. Transcription of UQCRC1 is repressed by the nuclear protein methyl-CpG-binding protein-2 (MeCP2).
Alternative Name:
QCR1, UQCR1, D3S3191,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: UQCRC1 polyclonal antibody detects endogenous levels of UQCRC1 protein.
Immunogen:
Recombinant protein of human UQCRC1.
MW: ~ 53 kDa
Swis Prot.: P31930
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
UQCRC1, or Ubiquinol-cytochrome-c reductase complex core protein 1, is a core subunit of the mitochondrial respiratory complex III. It is the largest nuclear encoded subunit of the complex. UQCRC1 plays a key role in mitochondria-to-nucleus retrograde response and is involved in the mitochondrial proton gradient formation. It has also shown to interact with Nogo, an inhibitor of neurite growth after spinal cord injury. UQCRC1 has been found at high expression levels in breast and ovarian tumors, positively correlating with Cox-2 expression. Transcription of UQCRC1 is repressed by the nuclear protein methyl-CpG-binding protein-2 (MeCP2).
Alternative Name:
QCR1, UQCR1, D3S3191,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: UQCRC1 polyclonal antibody detects endogenous levels of UQCRC1 protein.
Immunogen:
Recombinant protein of human UQCRC1.
MW: ~ 53 kDa
Swis Prot.: P31930
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review