URM1 Blocking Peptide (N-term)

Background:
Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, which include SUMO, ISG15, Nedd8, and Atg8, function as critical regulators of many cellular processes, including transcription, DNA repair, signal transduction, autophagy, and cell-cycle control. A growing body of data also implicates the dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery in the etiology and progression of a number of human diseases. URM1 is a ubiquitin-like modifier protein.

Other Names:
Ubiquitin-related modifier 1 {ECO:0000255|HAMAP-Rule:MF_03048}, URM1 {ECO:0000255|HAMAP-Rule:MF_03048}, C9orf74

Target/Specificity:
The synthetic peptide sequence is selected from aa 23-40 of HUMAN URM1

Gene Name: URM1 {ECO:0000255|HAMAP-Rule:MF_03048}

Gene ID: 81605
Primary Accession: Q9BTM9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.