USP14 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP19898b
Background:
This gene encodes a member of the ubiquitin-specificprocessing (UBP) family of proteases that is a deubiquitinatingenzyme (DUB) with His and Cys domains. This protein is located inthe cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fusedprecursors and ubiquitinylated proteins. Mice with a mutation thatresults in reduced expression of the ortholog of this protein areretarded for growth, develop severe tremors by 2 to 3 weeks of agefollowed by hindlimb paralysis and death by 6 to 10 weeks of age.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
Other Names:
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14, TGT
Target/Specificity:
The synthetic peptide sequence is selected from aa 370-383 of HUMAN USP14
Gene Name: USP14
Gene ID: 9097
Primary Accession: P54578
Other Accession: Q9JMA1; Q0IIF7; NP_005142.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the ubiquitin-specificprocessing (UBP) family of proteases that is a deubiquitinatingenzyme (DUB) with His and Cys domains. This protein is located inthe cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fusedprecursors and ubiquitinylated proteins. Mice with a mutation thatresults in reduced expression of the ortholog of this protein areretarded for growth, develop severe tremors by 2 to 3 weeks of agefollowed by hindlimb paralysis and death by 6 to 10 weeks of age.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
Other Names:
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14, TGT
Target/Specificity:
The synthetic peptide sequence is selected from aa 370-383 of HUMAN USP14
Gene Name: USP14
Gene ID: 9097
Primary Accession: P54578
Other Accession: Q9JMA1; Q0IIF7; NP_005142.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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