USP5 antibody (clone 2C8), anti-human
€435.00
In stock
SKU
AC-AT4495a
Catalog Number: AC-AT4495a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4495a">Request Information
Background:
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
Other Names:
Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, ISOT
Antigen Type:
Recombinant Protein
Gene Name: USP5
Gene ID: 8078
NCBI Accession: NP_001092006.1;NP_003472.2
Primary Accession: P45974
Other Accession: NM_003481
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
Other Names:
Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, ISOT
Antigen Type:
Recombinant Protein
Gene Name: USP5
Gene ID: 8078
NCBI Accession: NP_001092006.1;NP_003472.2
Primary Accession: P45974
Other Accession: NM_003481
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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