UVRAG Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP1850c
Background:
UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Other Names:
UV radiation resistance-associated gene protein, p63, UVRAG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1850c was selected from the Center region of human Autophagy UVRAG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UVRAG
Gene ID: 7405
Primary Accession: Q9P2Y5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Other Names:
UV radiation resistance-associated gene protein, p63, UVRAG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1850c was selected from the Center region of human Autophagy UVRAG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: UVRAG
Gene ID: 7405
Primary Accession: Q9P2Y5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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