VANGL2 Blocking Peptide (C-Term)
€363.00
In stock
SKU
AC-BP21414b
Background:
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Other Names:
Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1
Target/Specificity:
The synthetic peptide sequence is selected from aa 376-390 of HUMAN VANGL2
Gene Name: VANGL2
Gene ID: 57216
Primary Accession: Q9ULK5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Other Names:
Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1
Target/Specificity:
The synthetic peptide sequence is selected from aa 376-390 of HUMAN VANGL2
Gene Name: VANGL2
Gene ID: 57216
Primary Accession: Q9ULK5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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