VASP (phospho-S238) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4723
Background:
VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.
Alternative Name:
Vasodilator-stimulated phosphoprotein, VASP
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: p-VASP (S238) polyclonal antibody detects endogenous levels of VASP protein only when phosphorylated at Ser238.
Immunogen:
Synthetic phosphopeptide derived from human VASP around the phosphorylation site of Serine 238.
MW: ~ 40, 48 kDa
Swis Prot.: P50552
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.
Alternative Name:
Vasodilator-stimulated phosphoprotein, VASP
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: p-VASP (S238) polyclonal antibody detects endogenous levels of VASP protein only when phosphorylated at Ser238.
Immunogen:
Synthetic phosphopeptide derived from human VASP around the phosphorylation site of Serine 238.
MW: ~ 40, 48 kDa
Swis Prot.: P50552
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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