VASP (phospho Ser238) Polyclonal Antibody

Background:
vasodilator-stimulated phosphoprotein(VASP) Homo sapiens Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008],

Alternative Names:
VASP, Vasodilator-stimulated phosphoprotein, VASP

Immunogen: The antiserum was produced against synthesized peptide derived from human VASP around the phosphorylation site of Ser238. AA range:206-255

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 46+50

GeneID: VASP

Storage: -20°C/1 year

NOTE: For Research Use Only