FBXO7 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP74008
Background:
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Other Names:
FBXO7 FBX7
Antigen Type: synthetic peptide
Antigen Type: FBXO7
Gene ID: 25793
Primary Accession: Q9Y3I1
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Other Names:
FBXO7 FBX7
Antigen Type: synthetic peptide
Antigen Type: FBXO7
Gene ID: 25793
Primary Accession: Q9Y3I1
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