Vav3 (phospho Tyr173) Polyclonal Antibody

Background:
vav guanine nucleotide exchange factor 3(VAV3) Homo sapiens This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Alternative Names:
VAV3, Guanine nucleotide exchange factor VAV3, VAV-3

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 100

GeneID: VAV3

Storage: -20°C/1 year

NOTE: For Research Use Only