VDR Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14793c
Background:
This gene encodes the nuclear hormone receptor for vitaminD3. This receptor also functions as a receptor for the secondarybile acid lithocholic acid. The receptor belongs to the family oftrans-acting transcriptional regulatory factors and shows sequencesimilarity to the steroid and thyroid hormone receptors. Downstreamtargets of this nuclear hormone receptor are principally involvedin mineral metabolism though the receptor regulates a variety ofother metabolic pathways, such as those involved in the immuneresponse and cancer. Mutations in this gene are associated withtype II vitamin D-resistant rickets. A single nucleotidepolymorphism in the initiation codon results in an alternatetranslation start site three codons downstream. Alternativesplicing results in multiple transcript variants encoding the sameprotein.
Other Names:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
Gene Name: VDR (HGNC:12679)
Gene ID: 7421
Primary Accession: P11473
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the nuclear hormone receptor for vitaminD3. This receptor also functions as a receptor for the secondarybile acid lithocholic acid. The receptor belongs to the family oftrans-acting transcriptional regulatory factors and shows sequencesimilarity to the steroid and thyroid hormone receptors. Downstreamtargets of this nuclear hormone receptor are principally involvedin mineral metabolism though the receptor regulates a variety ofother metabolic pathways, such as those involved in the immuneresponse and cancer. Mutations in this gene are associated withtype II vitamin D-resistant rickets. A single nucleotidepolymorphism in the initiation codon results in an alternatetranslation start site three codons downstream. Alternativesplicing results in multiple transcript variants encoding the sameprotein.
Other Names:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
Gene Name: VDR (HGNC:12679)
Gene ID: 7421
Primary Accession: P11473
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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