VDR monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2082a
Catalog Number: AC-AM2082a
Size: 100 µl
Isotype: mouse IgA
Clone Name: 517CT23.5.1
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgA
Clone Name: 517CT23.5.1
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Other Names:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
Target/Specificity:
Purified His-tagged VDR protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: VDR (HGNC:12679)
Gene ID: 7421
Primary Accession: P11473
NCBI Accession: NP_000367.1;NP_001017535.1;NP_001017536.1
Other Accession: NP_000367.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Other Names:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
Target/Specificity:
Purified His-tagged VDR protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: VDR (HGNC:12679)
Gene ID: 7421
Primary Accession: P11473
NCBI Accession: NP_000367.1;NP_001017535.1;NP_001017536.1
Other Accession: NP_000367.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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