VEGFA Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12184c
Background:
This gene is a member of the PDGF/VEGF growth factorfamily and encodes a protein that is often found as a disulfidelinked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects,including mediating increased vascular permeability, inducingangiogenesis, vasculogenesis and endothelial cell growth, promotingcell migration, and inhibiting apoptosis. Elevated levels of thisprotein is linked to POEMS syndrome, also known as Crow-Fukasesyndrome. Mutations in this gene have been associated withproliferative and nonproliferative diabetic retinopathy.Alternatively spliced transcript variants, encoding either freelysecreted or cell-associated isoforms, have been characterized.There is also evidence for the use of non-AUG (CUG) translationinitiation sites upstream of, and in-frame with the first AUG,leading to additional isoforms.
Other Names:
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGFA, VEGF
Gene Name: VEGFA
Gene ID: 7422
Primary Accession: P15692
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the PDGF/VEGF growth factorfamily and encodes a protein that is often found as a disulfidelinked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects,including mediating increased vascular permeability, inducingangiogenesis, vasculogenesis and endothelial cell growth, promotingcell migration, and inhibiting apoptosis. Elevated levels of thisprotein is linked to POEMS syndrome, also known as Crow-Fukasesyndrome. Mutations in this gene have been associated withproliferative and nonproliferative diabetic retinopathy.Alternatively spliced transcript variants, encoding either freelysecreted or cell-associated isoforms, have been characterized.There is also evidence for the use of non-AUG (CUG) translationinitiation sites upstream of, and in-frame with the first AUG,leading to additional isoforms.
Other Names:
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGFA, VEGF
Gene Name: VEGFA
Gene ID: 7422
Primary Accession: P15692
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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