Vimentin (clone ), anti-human, mouse, rat
€428.00
In stock
SKU
MB9006
Background:
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain, α-helical, coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently coexpressed with other members of the intermediate filament family, such as the cytokeratins, in neoplasms including melanoma and breast carcinoma.
Alternative Name:
Vimentin, VIM
Application Dilution: WB: 1:2000-1:5000, ICC: 1:200, IHC: 1:200, FC: 1:50-1:100
Specificity: This antibody detects endogenous levels of Vimentin and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of Vimentin.
MW: ~ 54 kDa
Swis Prot.: P08670
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG1. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain, α-helical, coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently coexpressed with other members of the intermediate filament family, such as the cytokeratins, in neoplasms including melanoma and breast carcinoma.
Alternative Name:
Vimentin, VIM
Application Dilution: WB: 1:2000-1:5000, ICC: 1:200, IHC: 1:200, FC: 1:50-1:100
Specificity: This antibody detects endogenous levels of Vimentin and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of Vimentin.
MW: ~ 54 kDa
Swis Prot.: P08670
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG1. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review