Vitronectin (clone HV23), anti-human, bovine, dog, cat, horse, goat
€829.00
In stock
SKU
250265
Protein Family: CAM Ligands, Receptors and Channels, Cell Adhesion Molecules
Pathway and Disease: Cancers, Signaling Molecules and Interaction, Cell Motility, Cell Growth and Death
Description:
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognises fibronectin. This antibody is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). This antibody reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse.
Alternate Names: Vitronectin, VTN, VN, Serum-spreading factor, S-protein, V75, Somatomedin B
Application Notes: Product Cat. No. 250265 binds nearly as well to native vitronectin as to denatured. Product Cat. No. 250265 is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding. Product Cat. No. 250265 also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well. E: 1:30,000; WB: 1:50-1:200
Accession No.: P04004
Antigen: Human vitronectin purified from plasma by heparin-affinity chromatography
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Signaling Molecules and Interaction, Cell Motility, Cell Growth and Death
Description:
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognises fibronectin. This antibody is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). This antibody reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse.
Alternate Names: Vitronectin, VTN, VN, Serum-spreading factor, S-protein, V75, Somatomedin B
Application Notes: Product Cat. No. 250265 binds nearly as well to native vitronectin as to denatured. Product Cat. No. 250265 is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding. Product Cat. No. 250265 also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well. E: 1:30,000; WB: 1:50-1:200
Accession No.: P04004
Antigen: Human vitronectin purified from plasma by heparin-affinity chromatography
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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