VNN1 antibody (clone 400000000000), anti-human
€435.00
In stock
SKU
AC-AT4516a
Catalog Number: AC-AT4516a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IF, E
Request Information AC-AT4516a">Request Information
Background:
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Other Names:
Pantetheinase, Pantetheine hydrolase, Tiff66, Vascular non-inflammatory molecule 1, Vanin-1, VNN1
Antigen Type:
Recombinant Protein
Gene Name: VNN1
Gene ID: 8876
NCBI Accession: NP_004657.2
Primary Accession: O95497
Other Accession: NM_004666
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Other Names:
Pantetheinase, Pantetheine hydrolase, Tiff66, Vascular non-inflammatory molecule 1, Vanin-1, VNN1
Antigen Type:
Recombinant Protein
Gene Name: VNN1
Gene ID: 8876
NCBI Accession: NP_004657.2
Primary Accession: O95497
Other Accession: NM_004666
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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