von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (clone IIIE2.34 ), anti-human
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In stock
SKU
AC-AH12521
Catalog Number: AC-AH12521
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: IIIE2.34
Applications: WB, IHC, IF, FC, IP
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: IIIE2.34
Applications: WB, IHC, IF, FC, IP
Datasheet
Request Information
Background:
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi’s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Other Names:
von Willebrand factor, vWF, von Willebrand antigen 2, von Willebrand antigen II, VWF, F8VWF
Gene Name: VWF
Gene ID: 7450
Primary Accession: P04275
Other Accession: 7450, 440848
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi’s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Other Names:
von Willebrand factor, vWF, von Willebrand antigen 2, von Willebrand antigen II, VWF, F8VWF
Gene Name: VWF
Gene ID: 7450
Primary Accession: P04275
Other Accession: 7450, 440848
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