VPS4B Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13813b
Background:
The protein encoded by this gene is a member of the AAAprotein family (ATPases associated with diverse cellularactivities), and is the homolog of the yeast Vps4 protein. Inhumans, two paralogs of the yeast protein have been identified. Theformer share a high degree of aa sequence similarity with eachother, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1(suppressor of K+ transport defect 1) has been shown to be a yeastVps4 ortholog. Functional studies indicate that both human paralogsassociate with the endosomal compartments, and are involved inintracellular protein trafficking, similar to Vps4 protein inyeast. The gene encoding this paralog has been mapped to chromosome18; the gene for the other resides on chromosome 16. [provided byRefSeq].
Other Names:
Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13813b was selected from the C-term region of VPS4B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VPS4B (HGNC:10895)
Gene ID: 9525
Primary Accession: O75351
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of the AAAprotein family (ATPases associated with diverse cellularactivities), and is the homolog of the yeast Vps4 protein. Inhumans, two paralogs of the yeast protein have been identified. Theformer share a high degree of aa sequence similarity with eachother, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1(suppressor of K+ transport defect 1) has been shown to be a yeastVps4 ortholog. Functional studies indicate that both human paralogsassociate with the endosomal compartments, and are involved inintracellular protein trafficking, similar to Vps4 protein inyeast. The gene encoding this paralog has been mapped to chromosome18; the gene for the other resides on chromosome 16. [provided byRefSeq].
Other Names:
Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13813b was selected from the C-term region of VPS4B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VPS4B (HGNC:10895)
Gene ID: 9525
Primary Accession: O75351
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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