VRK3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP7410c
Background:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Inactive serine/threonine-protein kinase VRK3, Serine/threonine-protein pseudokinase VRK3, Vaccinia-related kinase 3, VRK3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7410c was selected from the Center region of human VRK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VRK3
Gene ID: 51231
Primary Accession: Q8IV63
Other Accession: Q9P2V8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Inactive serine/threonine-protein kinase VRK3, Serine/threonine-protein pseudokinase VRK3, Vaccinia-related kinase 3, VRK3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7410c was selected from the Center region of human VRK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VRK3
Gene ID: 51231
Primary Accession: Q8IV63
Other Accession: Q9P2V8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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