WASF2 monoclonal, anti-human, mouse, rat

Description: Anti-WASF2 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex..

Other Names: Actin-binding protein WASF2, Protein WAVE-2, Verprolin homology domain-containing protein 2, Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, WASF2 (HGNC:12733)

Clone Name(s):
Clone: FFG-23

Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. At the interface between the lamellipodial actin meshwork and the membrane..

Tissue Specificity: Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle..

Gene ID: 10163

Immunogen: A synthesized peptide derived from human WASF2

Calculated MW: 54284

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.