WDR5 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP21036c
Background:
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Other Names:
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3
Target/Specificity:
The synthetic peptide sequence is selected from aa 321-334 of HUMAN WDR5
Gene Name: WDR5
Gene ID: 11091
Primary Accession: P61964
Other Accession: Q9V3J8; Q498M4; P61965; Q2KIG2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Other Names:
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3
Target/Specificity:
The synthetic peptide sequence is selected from aa 321-334 of HUMAN WDR5
Gene Name: WDR5
Gene ID: 11091
Primary Accession: P61964
Other Accession: Q9V3J8; Q498M4; P61965; Q2KIG2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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