WDR77 (clone 8A10-C10-E8), anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV12071-100
Catalog Number: AC-ABV12071-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IF
Datasheet
Request Information
Size: 100 µg
Host: Mouse IgG
Applications: WB, IF
Datasheet
Request Information
Background:
Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Other Names:
Methylosome protein 50, MEP-50, Androgen receptor cofactor p44, WD repeat-containing protein 77, p44/Mep50, MEP50, WD45
Primary Accession: Q9BQA1
Gene Name: WDR77
Gene ID: 79084
Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Other Names:
Methylosome protein 50, MEP-50, Androgen receptor cofactor p44, WD repeat-containing protein 77, p44/Mep50, MEP50, WD45
Primary Accession: Q9BQA1
Gene Name: WDR77
Gene ID: 79084
| Is Featured? | No |
|---|
Write Your Own Review