WDR77 (clone 8A10-C10-E8), anti-human, mouse, rat

Background:
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061).This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al.,2002 [PubMed 11756452]).[supplied by OMIM,Mar 2008]

Synonyms: HKMT1069, MEP-50, MEP50, Nbla10071, p44, p44/Mep50

Cellular Location: Cytoplasm Nucleus

Immunogen:
Purified recombinant human WDR77 protein fragments expressed in E.coli.

Gene Symbol: WDR77

Gene ID: 79084

Swiss prot: Q9BQA1

Calculated MW: 42kDa

Recommended dilution:
WB 1:1000, ICC 1:100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.