WDR82 Blocking Peptide (N-term)

Background:
Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Other Names:
WD repeat-containing protein 82, Protein TMEM113, Swd2, WDR82, TMEM113, WDR82A

Target/Specificity:
The synthetic peptide sequence is selected from aa 50-65 of HUMAN WDR82

Gene Name: WDR82 {ECO:0000303|PubMed:17998332, ECO:0000312|HGNC:HGNC:28826}

Gene ID: 80335
Primary Accession: Q6UXN9
Other Accession: Q8BFQ4; Q6NV31; Q5ZMV7; Q58E77; Q640J6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.