WHSC2 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14802c
Background:
This gene is expressed ubiquitously with higher levels infetal than in adult tissues. It encodes a protein sharing 93%sequence identity with the mouse protein. Wolf-Hirschhorn syndrome(WHS) is a malformation syndrome associated with a hemizygousdeletion of the distal short arm of chromosome 4. This gene ismapped to the 165 kb WHS critical region, and may play a role inthe phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encodedprotein is found to be capable of reacting with HLA-A2-restrictedand tumor-specific cytotoxic T lymphocytes, suggesting a target foruse in specific immunotherapy for a large number of cancerpatients. This protein has also been shown to be a member of theNELF (negative elongation factor) protein complex that participatesin the regulation of RNA polymerase II transcription elongation.
Other Names:
Negative elongation factor A, NELF-A, Wolf-Hirschhorn syndrome candidate 2 protein, NELFA, WHSC2
Gene Name: NELFA
Gene ID: 7469
Primary Accession: Q9H3P2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is expressed ubiquitously with higher levels infetal than in adult tissues. It encodes a protein sharing 93%sequence identity with the mouse protein. Wolf-Hirschhorn syndrome(WHS) is a malformation syndrome associated with a hemizygousdeletion of the distal short arm of chromosome 4. This gene ismapped to the 165 kb WHS critical region, and may play a role inthe phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encodedprotein is found to be capable of reacting with HLA-A2-restrictedand tumor-specific cytotoxic T lymphocytes, suggesting a target foruse in specific immunotherapy for a large number of cancerpatients. This protein has also been shown to be a member of theNELF (negative elongation factor) protein complex that participatesin the regulation of RNA polymerase II transcription elongation.
Other Names:
Negative elongation factor A, NELF-A, Wolf-Hirschhorn syndrome candidate 2 protein, NELFA, WHSC2
Gene Name: NELFA
Gene ID: 7469
Primary Accession: Q9H3P2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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